Week 2 · Thu, Sep 17
The Bills beat the Lions 41–31 at home in Buffalo, moving to 2–0. The Lions fell to 1–1.
For the Bills, Josh Allen went 20-for-31 for 248 yards with 3 touchdowns. James Cook ran for 135 yards on 21 carries and scored a touchdown. Dalton Kincaid caught 7 passes for 95 yards and a touchdown.
For the Lions, Jared Goff went 26-for-38 for 327 yards with 4 touchdowns. Amon-Ra St. Brown caught 9 passes for 142 yards and 2 touchdowns.
On defense, Greg Rousseau (Bills) had 2 sacks.
Week 2 · Sun, Sep 20
The Panthers beat the Falcons 34–3 in Atlanta, moving to 1–1. The Falcons fell to 0–2.
For the Panthers, Bryce Young went 23-for-36 for 287 yards with 3 touchdowns. Tetairoa McMillan caught 5 passes for 101 yards.
For the Falcons, Cooper Rush went 10-for-17 for 86 yards with 2 interceptions. Jack Strand also played, going 8-for-15 for 59 yards with 1 interception. Bijan Robinson ran for 72 yards on 16 carries.
On defense, Devin Lloyd (Panthers) had 1 sack, 2 interceptions and a defensive touchdown and Bobby Okereke (Panthers) had an interception.
Week 2 · Sun, Sep 20
The Saints beat the Ravens 24–17 in Baltimore, moving to 1–1. The Ravens fell to 1–1.
For the Saints, Tyler Shough went 27-for-34 for 252 yards with 1 touchdown. Chris Olave caught 8 passes for 86 yards and a touchdown.
For the Ravens, Lamar Jackson went 21-for-31 for 235 yards with 1 touchdown and 1 interception. Derrick Henry ran for 68 yards on 16 carries and scored a touchdown. Rashod Bateman caught 7 passes for 88 yards and a touchdown.
On defense, Julian Blackmon (Saints) had an interception.
Week 2 · Sun, Sep 20
The Vikings beat the Bears 9–3 in Chicago, moving to 2–0. The Bears fell to 1–1.
For the Vikings, Carson Wentz went 11-for-20 for 143 yards. Aaron Jones ran for 105 yards on 23 carries.
For the Bears, Caleb Williams went 15-for-26 for 138 yards with 1 interception.
On defense, Byron Murphy (Vikings) had an interception and Dallas Turner (Vikings) had 2 sacks.
Week 2 · Sun, Sep 20
The Bengals beat the Texans 20–6 in Houston, moving to 2–0. The Texans fell to 0–2.
For the Bengals, Joe Burrow went 20-for-31 for 207 yards with 2 touchdowns. Chase Brown ran for 80 yards on 20 carries. Tee Higgins caught 5 passes for 95 yards.
For the Texans, C.J. Stroud went 30-for-55 for 353 yards. Dalton Schultz caught 12 passes for 140 yards.
On defense, Cedric Johnson (Bengals) had 2 sacks.
Week 2 · Sun, Sep 20
The Patriots beat the Steelers 20–3 at home in New England, moving to 1–1. The Steelers fell to 1–1.
For the Patriots, Drake Maye went 14-for-22 for 208 yards with 1 interception. TreVeyon Henderson ran for 76 yards on 16 carries and scored a touchdown. Romeo Doubs caught 3 passes for 96 yards.
For the Steelers, Aaron Rodgers went 23-for-39 for 187 yards with 1 interception.
On defense, Patrick Queen (Steelers) had an interception and Gabe Jacas (Patriots) had an interception.
Week 2 · Sun, Sep 20
The Packers beat the Jets 20–17 in overtime in New York, moving to 1–1. The Jets fell to 1–1.
For the Packers, Jordan Love went 16-for-29 for 145 yards with 2 touchdowns.
For the Jets, Geno Smith went 27-for-41 for 247 yards with 1 touchdown. Breece Hall caught 5 passes for 63 yards.
Week 2 · Sun, Sep 20
The Browns beat the Buccaneers 23–19 in Tampa Bay, moving to 1–1. The Buccaneers fell to 0–2.
For the Browns, Deshaun Watson went 24-for-30 for 238 yards with 2 touchdowns. Denzel Boston caught 5 passes for 95 yards and a touchdown.
For the Buccaneers, Baker Mayfield went 21-for-34 for 182 yards with 1 touchdown and 1 interception. Bucky Irving ran for 89 yards on 17 carries.
On defense, Myles Harden (Browns) had an interception.
Week 2 · Sun, Sep 20
The Eagles beat the Titans 24–20 in Tennessee, moving to 2–0. The Titans fell to 0–2.
For the Eagles, Jalen Hurts went 26-for-37 for 264 yards with 2 touchdowns and 2 interceptions. Tank Bigsby ran for 33 yards on 13 carries and scored a touchdown. DeVonta Smith caught 10 passes for 117 yards and a touchdown.
For the Titans, Cam Ward went 13-for-20 for 183 yards. Tony Pollard ran for 64 yards on 14 carries. Elic Ayomanor caught 2 passes for 69 yards.
On defense, Amani Hooker (Titans) had an interception and Marcus Harris (Titans) had an interception.
Week 2 · Sun, Sep 20
The Broncos beat the Jaguars 20–13 at home in Denver, moving to 1–1. The Jaguars fell to 1–1.
For the Broncos, Bo Nix went 22-for-31 for 288 yards with 1 touchdown and 1 interception. Jonah Coleman ran for 39 yards on 10 carries and scored a touchdown. Jaylen Waddle caught 8 passes for 138 yards.
For the Jaguars, Trevor Lawrence went 17-for-29 for 189 yards with 1 interception. Bhayshul Tuten ran for 65 yards on 13 carries and scored a touchdown. Parker Washington caught 7 passes for 98 yards.
On defense, Jourdan Lewis (Jaguars) had an interception and Riley Moss (Broncos) had an interception.
Week 2 · Sun, Sep 20
The Raiders beat the Chargers 26–14 in Los Angeles, moving to 2–0. The Chargers fell to 0–2.
For the Raiders, Kirk Cousins went 19-for-29 for 253 yards with 3 touchdowns and 1 interception. Tre Tucker caught 5 passes for 119 yards and a touchdown.
For the Chargers, Justin Herbert went 15-for-27 for 192 yards with 1 touchdown and 2 interceptions. Omarion Hampton ran for 94 yards on 23 carries and scored a touchdown.
On defense, Hezekiah Masses (Raiders) had 2 interceptions and Cam Hart (Chargers) had an interception.
Week 2 · Sun, Sep 20
The Seahawks beat the Cardinals 31–7 in Arizona, moving to 2–0. The Cardinals fell to 1–1.
For the Seahawks, Drew Lock went 19-for-26 for 235 yards with 3 touchdowns. Emanuel Wilson ran for 92 yards on 21 carries. Jaxon Smith-Njigba caught 9 passes for 155 yards and 3 touchdowns.
For the Cardinals, Jacoby Brissett went 17-for-28 for 95 yards with 1 touchdown and 1 interception. Trey McBride caught 8 passes for 41 yards and a touchdown.
On defense, Julian Love (Seahawks) had an interception.
Week 2 · Sun, Sep 20
The Cowboys beat the Commanders 37–20 at home in Dallas, moving to 1–1. The Commanders fell to 0–2.
For the Cowboys, Dak Prescott went 26-for-31 for 279 yards with 4 touchdowns. CeeDee Lamb caught 8 passes for 153 yards and 2 touchdowns.
For the Commanders, Jayden Daniels went 11-for-17 for 96 yards with 1 touchdown. Marcus Mariota also played, going 11-for-16 for 111 yards with 1 touchdown.
Week 2 · Sun, Sep 20
The 49ers beat the Dolphins 35–13 at home in San Francisco, moving to 2–0. The Dolphins fell to 0–2.
For the 49ers, Brock Purdy went 20-for-22 for 287 yards with 2 touchdowns. George Kittle caught 4 passes for 80 yards and a touchdown.
For the Dolphins, Malik Willis went 14-for-23 for 197 yards with 1 touchdown. De'Von Achane ran for 74 yards on 20 carries. Ryan Miller caught 1 pass for 77 yards and a touchdown.
Week 2 · Sun, Sep 20
The Chiefs beat the Colts 33–30 in overtime at home in Kansas City, moving to 2–0. The Colts fell to 0–2.
For the Chiefs, Patrick Mahomes went 32-for-47 for 382 yards with 3 touchdowns. Kenneth Walker III ran for 117 yards on 24 carries. Travis Kelce caught 9 passes for 101 yards and a touchdown.
For the Colts, Daniel Jones went 22-for-31 for 210 yards with 1 touchdown and 1 interception. Jonathan Taylor ran for 92 yards on 24 carries and scored 2 touchdowns. Josh Downs caught 7 passes for 72 yards.
On defense, Kristian Fulton (Chiefs) had an interception.
Week 2 · Mon, Sep 21
The Rams beat the Giants 28–6 at home in Los Angeles, moving to 1–1. The Giants fell to 1–1.
For the Rams, Matthew Stafford went 22-for-31 for 327 yards with 4 touchdowns and 1 interception. Kyren Williams ran for 85 yards on 12 carries. Davante Adams caught 8 passes for 195 yards and 2 touchdowns.
For the Giants, Jameis Winston went 11-for-27 for 111 yards with 1 interception.
On defense, Jevon Holland (Giants) had an interception and Trent McDuffie (Rams) had an interception.