Lineup Field

49ers at Chiefs: Starting Lineups, Week 16

Kickoff Sun, Dec 27, 4:25 PM ET

49ers quarterback Brock Purdy against Chiefs quarterback Patrick Mahomes. Latest depth charts (Nov 4, 2026, 10:20 AM ET). They can change until kickoff.

Preview

The 49ers (6–1) visit the Chiefs (5–2). The 49ers score 28.1 points a game (4th in the NFL) and allow 19.9 (6th); the Chiefs score 23.9 (11th) and allow 18.7 (4th).

By EPA per play, the 49ers offense ranks 1st against a Chiefs defense that ranks 11th, and the Chiefs offense ranks 4th against the 49ers defense's 8th. Power rankings: 49ers 2nd, Chiefs 3rd.

Last three games: 49ers W 32–29 at Seahawks, W 23–17 vs Commanders, L 20–29 at Falcons; Chiefs W 22–6 vs Chargers, L 3–20 at Seahawks, L 24–28 at Broncos.

49ers depth chart · Chiefs depth chart · All Week 16 games

49ers offense vs Chiefs defense

49ers this season before this game: shotgun 49%, under center 50%, pistol 0% · one back 57%, two backs 28%, empty 14% · motion 76% (416 charted snaps, 7 games).

San Francisco 49ers offense in a 3 WR set against the Kansas City Chiefs defenseChiefs defense: LDE George Karlaftis, LDT Chris Jones, RDT Khyiris Tonga, RDE Felix Anudike-Uzomah, WLB Drue Tranquill, MLB Nick Bolton, SLB Jeffrey Bassa, LCB Nohl Williams, SS Chamarri Conner, FS Alohi Gilman, RCB Mansoor Delane. 49ers offense: WR Mike Evans, WR Deebo Samuel, LT Trent Williams, LG Connor Colby, C Jake Brendel, RG Dominick Puni, RT Colton McKivitz, WR Jordan Watkins, QB Brock Purdy, TE George Kittle, RB Christian McCaffreyChiefs defense49ers offense#56LDEKarlaftis2 · Gillotte#95LDTJones2 · Woods#92RDTTonga2 · Eason#91RDEAnudike-Uzomah2 · Thomas#23WLBTranquillno backup listed#32MLBBolton2 · Cochrane#31SLBBassa2 · McDonald#20LCBWilliams2 · Roland-Wallace#27SSConner2 · Hicks#17FSGilman2 · Nwankpa#5RCBDelane2 · Fulton#5WREvans2 · Cooks#19WRSamuel2 · Kirk#71LTWilliams2 · Lowe#75LGColby2 · Willis#64CBrendel2 · Patterson#77RGPuni2 · Willis#68RTMcKivitz2 · Cruz Jr.#17WRWatkins2 · Cowing#13QBPurdy2 · Jones#85TEKittle2 · Farrell#23RBMcCaffrey2 · Black

As the team lists it: three receivers, one tight end and one running back. Quarterback shown under center, where the 49ers lined him up on most snaps.

49ers offense, 3 WR

  1. WR#5 Mike EvansNext up: Brandin Cooks
  2. WR#19 Deebo SamuelNext up: Christian Kirk
  3. LT#71 Trent WilliamsNext up: Vederian Lowe
  4. LG#75 Connor ColbyNext up: Carver Willis
  5. C#64 Jake BrendelNext up: Jarrett Patterson
  6. RG#77 Dominick PuniNext up: Carver Willis
  7. RT#68 Colton McKivitzNext up: Enrique Cruz Jr.
  8. WR#17 Jordan WatkinsNext up: Jacob Cowing
  9. QB#13 Brock PurdyNext up: Mac Jones
  10. TE#85 George KittleNext up: Luke Farrell
  11. RB#23 Christian McCaffreyNext up: Kaelon Black

Chiefs defense

  1. LDE#56 George KarlaftisNext up: Ashton Gillotte
  2. LDT#95 Chris JonesNext up: Peter Woods
  3. RDT#92 Khyiris TongaNext up: Bryson Eason
  4. RDE#91 Felix Anudike-UzomahNext up: R Mason Thomas
  5. WLB#23 Drue TranquillNo backup listed
  6. MLB#32 Nick BoltonNext up: Jack Cochrane
  7. SLB#31 Jeffrey BassaNext up: Cooper McDonald
  8. LCB#20 Nohl WilliamsNext up: Chris Roland-Wallace
  9. SS#27 Chamarri ConnerNext up: Jaden Hicks
  10. FS#17 Alohi GilmanNext up: Xavier Nwankpa
  11. RCB#5 Mansoor DelaneNext up: Kristian Fulton
San Francisco 49ers offense in a 2 TE set against the Kansas City Chiefs defenseChiefs defense: LDE George Karlaftis, LDT Chris Jones, RDT Khyiris Tonga, RDE Felix Anudike-Uzomah, WLB Drue Tranquill, MLB Nick Bolton, SLB Jeffrey Bassa, LCB Nohl Williams, SS Chamarri Conner, FS Alohi Gilman, RCB Mansoor Delane. 49ers offense: LT Trent Williams, LG Connor Colby, C Jake Brendel, RG Dominick Puni, RT Colton McKivitz, WR Mike Evans, WR Deebo Samuel, TE George Kittle, TE Luke Farrell, QB Brock Purdy, RB Christian McCaffreyChiefs defense49ers offense#56LDEKarlaftis2 · Gillotte#95LDTJones2 · Woods#92RDTTonga2 · Eason#91RDEAnudike-Uzomah2 · Thomas#23WLBTranquillno backup listed#32MLBBolton2 · Cochrane#31SLBBassa2 · McDonald#20LCBWilliams2 · Roland-Wallace#27SSConner2 · Hicks#17FSGilman2 · Nwankpa#5RCBDelane2 · Fulton#71LTWilliams2 · Lowe#75LGColby2 · Willis#64CBrendel2 · Patterson#77RGPuni2 · Willis#68RTMcKivitz2 · Cruz Jr.#5WREvans2 · Watkins#19WRSamuel2 · Cooks#85TEKittle2 · Willis#89TEFarrell2 · Tonges#13QBPurdy2 · Jones#23RBMcCaffrey2 · Black

Two tight ends: the top two receivers stay on the field and the second tight end lines up on the left end. Quarterback shown under center, where the 49ers lined him up on most snaps. Players beyond the listed starters come from the depth-chart order: this is who is most likely in, not a team announcement.

49ers offense, 2 TE

  1. LT#71 Trent WilliamsNext up: Vederian Lowe
  2. LG#75 Connor ColbyNext up: Carver Willis
  3. C#64 Jake BrendelNext up: Jarrett Patterson
  4. RG#77 Dominick PuniNext up: Carver Willis
  5. RT#68 Colton McKivitzNext up: Enrique Cruz Jr.
  6. WR#5 Mike EvansNext up: Jordan Watkins
  7. WR#19 Deebo SamuelNext up: Brandin Cooks
  8. TE#85 George KittleNext up: Brayden Willis
  9. TE#89 Luke FarrellNext up: Jake Tonges
  10. QB#13 Brock PurdyNext up: Mac Jones
  11. RB#23 Christian McCaffreyNext up: Kaelon Black

Chiefs defense

  1. LDE#56 George KarlaftisNext up: Ashton Gillotte
  2. LDT#95 Chris JonesNext up: Peter Woods
  3. RDT#92 Khyiris TongaNext up: Bryson Eason
  4. RDE#91 Felix Anudike-UzomahNext up: R Mason Thomas
  5. WLB#23 Drue TranquillNo backup listed
  6. MLB#32 Nick BoltonNext up: Jack Cochrane
  7. SLB#31 Jeffrey BassaNext up: Cooper McDonald
  8. LCB#20 Nohl WilliamsNext up: Chris Roland-Wallace
  9. SS#27 Chamarri ConnerNext up: Jaden Hicks
  10. FS#17 Alohi GilmanNext up: Xavier Nwankpa
  11. RCB#5 Mansoor DelaneNext up: Kristian Fulton
San Francisco 49ers offense in a I-form set against the Kansas City Chiefs defenseChiefs defense: LDE George Karlaftis, LDT Chris Jones, RDT Khyiris Tonga, RDE Felix Anudike-Uzomah, WLB Drue Tranquill, MLB Nick Bolton, SLB Jeffrey Bassa, LCB Nohl Williams, SS Chamarri Conner, FS Alohi Gilman, RCB Mansoor Delane. 49ers offense: LT Trent Williams, LG Connor Colby, C Jake Brendel, RG Dominick Puni, RT Colton McKivitz, WR Mike Evans, WR Deebo Samuel, TE George Kittle, QB Brock Purdy, FB Kyle Juszczyk, RB Christian McCaffreyChiefs defense49ers offense#56LDEKarlaftis2 · Gillotte#95LDTJones2 · Woods#92RDTTonga2 · Eason#91RDEAnudike-Uzomah2 · Thomas#23WLBTranquillno backup listed#32MLBBolton2 · Cochrane#31SLBBassa2 · McDonald#20LCBWilliams2 · Roland-Wallace#27SSConner2 · Hicks#17FSGilman2 · Nwankpa#5RCBDelane2 · Fulton#71LTWilliams2 · Lowe#75LGColby2 · Willis#64CBrendel2 · Patterson#77RGPuni2 · Willis#68RTMcKivitz2 · Cruz Jr.#5WREvans2 · Watkins#19WRSamuel2 · Cooks#85TEKittle2 · Farrell#13QBPurdy2 · Jones#44FBJuszczykno backup listed#23RBMcCaffrey2 · Black

I-formation: two receivers and one tight end, with the quarterback under center and a fullback and running back stacked behind him. Two-back sets: 28% of snaps this season before this game. Players beyond the listed starters come from the depth-chart order: this is who is most likely in, not a team announcement.

49ers offense, I-form

  1. LT#71 Trent WilliamsNext up: Vederian Lowe
  2. LG#75 Connor ColbyNext up: Carver Willis
  3. C#64 Jake BrendelNext up: Jarrett Patterson
  4. RG#77 Dominick PuniNext up: Carver Willis
  5. RT#68 Colton McKivitzNext up: Enrique Cruz Jr.
  6. WR#5 Mike EvansNext up: Jordan Watkins
  7. WR#19 Deebo SamuelNext up: Brandin Cooks
  8. TE#85 George KittleNext up: Luke Farrell
  9. QB#13 Brock PurdyNext up: Mac Jones
  10. FB#44 Kyle JuszczykNo backup listed
  11. RB#23 Christian McCaffreyNext up: Kaelon Black

Chiefs defense

  1. LDE#56 George KarlaftisNext up: Ashton Gillotte
  2. LDT#95 Chris JonesNext up: Peter Woods
  3. RDT#92 Khyiris TongaNext up: Bryson Eason
  4. RDE#91 Felix Anudike-UzomahNext up: R Mason Thomas
  5. WLB#23 Drue TranquillNo backup listed
  6. MLB#32 Nick BoltonNext up: Jack Cochrane
  7. SLB#31 Jeffrey BassaNext up: Cooper McDonald
  8. LCB#20 Nohl WilliamsNext up: Chris Roland-Wallace
  9. SS#27 Chamarri ConnerNext up: Jaden Hicks
  10. FS#17 Alohi GilmanNext up: Xavier Nwankpa
  11. RCB#5 Mansoor DelaneNext up: Kristian Fulton
San Francisco 49ers offense in a 4 WR set against the Kansas City Chiefs defenseChiefs defense: LDE George Karlaftis, LDT Chris Jones, RDT Khyiris Tonga, RDE Felix Anudike-Uzomah, WLB Drue Tranquill, MLB Nick Bolton, SLB Jeffrey Bassa, LCB Nohl Williams, SS Chamarri Conner, FS Alohi Gilman, RCB Mansoor Delane. 49ers offense: LT Trent Williams, LG Connor Colby, C Jake Brendel, RG Dominick Puni, RT Colton McKivitz, WR Mike Evans, WR Deebo Samuel, WR Jordan Watkins, WR Brandin Cooks, QB Brock Purdy, RB Christian McCaffreyChiefs defense49ers offense#56LDEKarlaftis2 · Gillotte#95LDTJones2 · Woods#92RDTTonga2 · Eason#91RDEAnudike-Uzomah2 · Thomas#23WLBTranquillno backup listed#32MLBBolton2 · Cochrane#31SLBBassa2 · McDonald#20LCBWilliams2 · Roland-Wallace#27SSConner2 · Hicks#17FSGilman2 · Nwankpa#5RCBDelane2 · Fulton#71LTWilliams2 · Lowe#75LGColby2 · Willis#64CBrendel2 · Patterson#77RGPuni2 · Willis#68RTMcKivitz2 · Cruz Jr.#5WREvans2 · Kirk#19WRSamuel2 · Cowing#17WRWatkins2 · Robinson#84WRCooks2 · Stribling#13QBPurdy2 · Jones#23RBMcCaffrey2 · Black

Four receivers and no tight end: the next receiver on the depth chart comes in. Quarterback shown under center, where the 49ers lined him up on most snaps. Empty-backfield sets: 14% of snaps this season before this game. Players beyond the listed starters come from the depth-chart order: this is who is most likely in, not a team announcement.

49ers offense, 4 WR

  1. LT#71 Trent WilliamsNext up: Vederian Lowe
  2. LG#75 Connor ColbyNext up: Carver Willis
  3. C#64 Jake BrendelNext up: Jarrett Patterson
  4. RG#77 Dominick PuniNext up: Carver Willis
  5. RT#68 Colton McKivitzNext up: Enrique Cruz Jr.
  6. WR#5 Mike EvansNext up: Christian Kirk
  7. WR#19 Deebo SamuelNext up: Jacob Cowing
  8. WR#17 Jordan WatkinsNext up: Demarcus Robinson
  9. WR#84 Brandin CooksNext up: De'Zhaun Stribling
  10. QB#13 Brock PurdyNext up: Mac Jones
  11. RB#23 Christian McCaffreyNext up: Kaelon Black

Chiefs defense

  1. LDE#56 George KarlaftisNext up: Ashton Gillotte
  2. LDT#95 Chris JonesNext up: Peter Woods
  3. RDT#92 Khyiris TongaNext up: Bryson Eason
  4. RDE#91 Felix Anudike-UzomahNext up: R Mason Thomas
  5. WLB#23 Drue TranquillNo backup listed
  6. MLB#32 Nick BoltonNext up: Jack Cochrane
  7. SLB#31 Jeffrey BassaNext up: Cooper McDonald
  8. LCB#20 Nohl WilliamsNext up: Chris Roland-Wallace
  9. SS#27 Chamarri ConnerNext up: Jaden Hicks
  10. FS#17 Alohi GilmanNext up: Xavier Nwankpa
  11. RCB#5 Mansoor DelaneNext up: Kristian Fulton

Defense shown in its base front.

Chiefs offense vs 49ers defense

Chiefs this season before this game: shotgun 59%, under center 37%, pistol 4% · one back 83%, two backs 15%, empty 2% · motion 59% (437 charted snaps, 7 games).

Kansas City Chiefs offense in a 3 WR set against the San Francisco 49ers defense49ers defense: LDE Keion White, LDT Osa Odighizuwa, RDT DeForest Buckner, RDE Nick Bosa, WLB Dre Greenlaw, MLB Fred Warner, SLB Jaden Dugger, LCB Renardo Green, SS Marques Sigle, FS Ji'Ayir Brown, RCB Deommodore Lenoir. Chiefs offense: WR Rashee Rice, WR Xavier Worthy, LT Kahlil Benson, LG Mike Caliendo, C Creed Humphrey, RG Trey Smith, RT Jaylon Moore, WR Cyrus Allen, QB Patrick Mahomes, TE Travis Kelce, RB Kenneth Walker III49ers defenseChiefs offense#56LDEWhite2 · Height#92LDTOdighizuwa2 · Valdez#99RDTBuckner2 · Halton#97RDEBosa2 · Williams#57WLBGreenlaw2 · Wallow#54MLBWarner2 · Bethune#53SLBDugger2 · Gifford#0LCBGreenno backup listed#36SSSigle2 · Mustapha#27FSBrown2 · Davis#2RCBLenoir2 · Prysock#4WRRice2 · Royals#1WRWorthy2 · Armstrong#70LTBenson2 · Moore#66LGCaliendo2 · Suamataia#52CHumphrey2 · Nourzad#65RGSmith2 · Caliendo#77RTMoore2 · Ezeudu#13WRAllen2 · Remigio#15QBMahomes2 · Fields#87TEKelce2 · Gray#9RBWalker III2 · Johnson

As the team lists it: three receivers, one tight end and one running back. Quarterback shown in the shotgun, where the Chiefs lined him up on most snaps.

Chiefs offense, 3 WR

  1. WR#4 Rashee RiceNext up: Jalen Royals
  2. WR#1 Xavier WorthyNext up: Andrew Armstrong
  3. LT#70 Kahlil BensonNext up: Jaylon Moore
  4. LG#66 Mike CaliendoNext up: Kingsley Suamataia
  5. C#52 Creed HumphreyNext up: Hunter Nourzad
  6. RG#65 Trey SmithNext up: Mike Caliendo
  7. RT#77 Jaylon MooreNext up: Joshua Ezeudu
  8. WR#13 Cyrus AllenNext up: Nikko Remigio
  9. QB#15 Patrick MahomesNext up: Justin Fields
  10. TE#87 Travis KelceNext up: Noah Gray
  11. RB#9 Kenneth Walker IIINext up: Emmett Johnson

49ers defense

  1. LDE#56 Keion WhiteNext up: Romello Height
  2. LDT#92 Osa OdighizuwaNext up: Sebastian Valdez
  3. RDT#99 DeForest BucknerNext up: Gracen Halton
  4. RDE#97 Nick BosaNext up: Mykel Williams
  5. WLB#57 Dre GreenlawNext up: Garret Wallow
  6. MLB#54 Fred WarnerNext up: Tatum Bethune
  7. SLB#53 Jaden DuggerNext up: Luke Gifford
  8. LCB#0 Renardo GreenNo backup listed
  9. SS#36 Marques SigleNext up: Malik Mustapha
  10. FS#27 Ji'Ayir BrownNext up: Ashtyn Davis
  11. RCB#2 Deommodore LenoirNext up: Ephesians Prysock
Kansas City Chiefs offense in a 2 TE set against the San Francisco 49ers defense49ers defense: LDE Keion White, LDT Osa Odighizuwa, RDT DeForest Buckner, RDE Nick Bosa, WLB Dre Greenlaw, MLB Fred Warner, SLB Jaden Dugger, LCB Renardo Green, SS Marques Sigle, FS Ji'Ayir Brown, RCB Deommodore Lenoir. Chiefs offense: LT Kahlil Benson, LG Mike Caliendo, C Creed Humphrey, RG Trey Smith, RT Jaylon Moore, WR Rashee Rice, WR Xavier Worthy, TE Travis Kelce, TE Noah Gray, QB Patrick Mahomes, RB Kenneth Walker III49ers defenseChiefs offense#56LDEWhite2 · Height#92LDTOdighizuwa2 · Valdez#99RDTBuckner2 · Halton#97RDEBosa2 · Williams#57WLBGreenlaw2 · Wallow#54MLBWarner2 · Bethune#53SLBDugger2 · Gifford#0LCBGreenno backup listed#36SSSigle2 · Mustapha#27FSBrown2 · Davis#2RCBLenoir2 · Prysock#70LTBenson2 · Moore#66LGCaliendo2 · Suamataia#52CHumphrey2 · Nourzad#65RGSmith2 · Caliendo#77RTMoore2 · Ezeudu#4WRRice2 · Allen#1WRWorthy2 · Royals#87TEKelce2 · Briningstool#83TEGray2 · Wiley#15QBMahomes2 · Fields#9RBWalker III2 · Johnson

Two tight ends: the top two receivers stay on the field and the second tight end lines up on the left end. Quarterback shown in the shotgun, where the Chiefs lined him up on most snaps. Players beyond the listed starters come from the depth-chart order: this is who is most likely in, not a team announcement.

Chiefs offense, 2 TE

  1. LT#70 Kahlil BensonNext up: Jaylon Moore
  2. LG#66 Mike CaliendoNext up: Kingsley Suamataia
  3. C#52 Creed HumphreyNext up: Hunter Nourzad
  4. RG#65 Trey SmithNext up: Mike Caliendo
  5. RT#77 Jaylon MooreNext up: Joshua Ezeudu
  6. WR#4 Rashee RiceNext up: Cyrus Allen
  7. WR#1 Xavier WorthyNext up: Jalen Royals
  8. TE#87 Travis KelceNext up: Jake Briningstool
  9. TE#83 Noah GrayNext up: Jared Wiley
  10. QB#15 Patrick MahomesNext up: Justin Fields
  11. RB#9 Kenneth Walker IIINext up: Emmett Johnson

49ers defense

  1. LDE#56 Keion WhiteNext up: Romello Height
  2. LDT#92 Osa OdighizuwaNext up: Sebastian Valdez
  3. RDT#99 DeForest BucknerNext up: Gracen Halton
  4. RDE#97 Nick BosaNext up: Mykel Williams
  5. WLB#57 Dre GreenlawNext up: Garret Wallow
  6. MLB#54 Fred WarnerNext up: Tatum Bethune
  7. SLB#53 Jaden DuggerNext up: Luke Gifford
  8. LCB#0 Renardo GreenNo backup listed
  9. SS#36 Marques SigleNext up: Malik Mustapha
  10. FS#27 Ji'Ayir BrownNext up: Ashtyn Davis
  11. RCB#2 Deommodore LenoirNext up: Ephesians Prysock
Kansas City Chiefs offense in a I-form set against the San Francisco 49ers defense49ers defense: LDE Keion White, LDT Osa Odighizuwa, RDT DeForest Buckner, RDE Nick Bosa, WLB Dre Greenlaw, MLB Fred Warner, SLB Jaden Dugger, LCB Renardo Green, SS Marques Sigle, FS Ji'Ayir Brown, RCB Deommodore Lenoir. Chiefs offense: LT Kahlil Benson, LG Mike Caliendo, C Creed Humphrey, RG Trey Smith, RT Jaylon Moore, WR Rashee Rice, WR Xavier Worthy, TE Travis Kelce, QB Patrick Mahomes, FB Ben VanSumeren, RB Kenneth Walker III49ers defenseChiefs offense#56LDEWhite2 · Height#92LDTOdighizuwa2 · Valdez#99RDTBuckner2 · Halton#97RDEBosa2 · Williams#57WLBGreenlaw2 · Wallow#54MLBWarner2 · Bethune#53SLBDugger2 · Gifford#0LCBGreenno backup listed#36SSSigle2 · Mustapha#27FSBrown2 · Davis#2RCBLenoir2 · Prysock#70LTBenson2 · Moore#66LGCaliendo2 · Suamataia#52CHumphrey2 · Nourzad#65RGSmith2 · Caliendo#77RTMoore2 · Ezeudu#4WRRice2 · Allen#1WRWorthy2 · Royals#87TEKelce2 · Gray#15QBMahomes2 · Fields#47FBVanSumerenno backup listed#9RBWalker III2 · Johnson

I-formation: two receivers and one tight end, with the quarterback under center and a fullback and running back stacked behind him. Two-back sets: 15% of snaps this season before this game. Players beyond the listed starters come from the depth-chart order: this is who is most likely in, not a team announcement.

Chiefs offense, I-form

  1. LT#70 Kahlil BensonNext up: Jaylon Moore
  2. LG#66 Mike CaliendoNext up: Kingsley Suamataia
  3. C#52 Creed HumphreyNext up: Hunter Nourzad
  4. RG#65 Trey SmithNext up: Mike Caliendo
  5. RT#77 Jaylon MooreNext up: Joshua Ezeudu
  6. WR#4 Rashee RiceNext up: Cyrus Allen
  7. WR#1 Xavier WorthyNext up: Jalen Royals
  8. TE#87 Travis KelceNext up: Noah Gray
  9. QB#15 Patrick MahomesNext up: Justin Fields
  10. FB#47 Ben VanSumerenNo backup listed
  11. RB#9 Kenneth Walker IIINext up: Emmett Johnson

49ers defense

  1. LDE#56 Keion WhiteNext up: Romello Height
  2. LDT#92 Osa OdighizuwaNext up: Sebastian Valdez
  3. RDT#99 DeForest BucknerNext up: Gracen Halton
  4. RDE#97 Nick BosaNext up: Mykel Williams
  5. WLB#57 Dre GreenlawNext up: Garret Wallow
  6. MLB#54 Fred WarnerNext up: Tatum Bethune
  7. SLB#53 Jaden DuggerNext up: Luke Gifford
  8. LCB#0 Renardo GreenNo backup listed
  9. SS#36 Marques SigleNext up: Malik Mustapha
  10. FS#27 Ji'Ayir BrownNext up: Ashtyn Davis
  11. RCB#2 Deommodore LenoirNext up: Ephesians Prysock
Kansas City Chiefs offense in a 4 WR set against the San Francisco 49ers defense49ers defense: LDE Keion White, LDT Osa Odighizuwa, RDT DeForest Buckner, RDE Nick Bosa, WLB Dre Greenlaw, MLB Fred Warner, SLB Jaden Dugger, LCB Renardo Green, SS Marques Sigle, FS Ji'Ayir Brown, RCB Deommodore Lenoir. Chiefs offense: LT Kahlil Benson, LG Mike Caliendo, C Creed Humphrey, RG Trey Smith, RT Jaylon Moore, WR Rashee Rice, WR Xavier Worthy, WR Cyrus Allen, WR Jalen Royals, QB Patrick Mahomes, RB Kenneth Walker III49ers defenseChiefs offense#56LDEWhite2 · Height#92LDTOdighizuwa2 · Valdez#99RDTBuckner2 · Halton#97RDEBosa2 · Williams#57WLBGreenlaw2 · Wallow#54MLBWarner2 · Bethune#53SLBDugger2 · Gifford#0LCBGreenno backup listed#36SSSigle2 · Mustapha#27FSBrown2 · Davis#2RCBLenoir2 · Prysock#70LTBenson2 · Moore#66LGCaliendo2 · Suamataia#52CHumphrey2 · Nourzad#65RGSmith2 · Caliendo#77RTMoore2 · Ezeudu#4WRRice2 · Armstrong#1WRWorthy2 · Remigio#13WRAllen2 · Thornton#11WRRoyals2 · Caldwell#15QBMahomes2 · Fields#9RBWalker III2 · Johnson

Four receivers and no tight end: the next receiver on the depth chart comes in. Quarterback shown in the shotgun, where the Chiefs lined him up on most snaps. Empty-backfield sets: 2% of snaps this season before this game. Players beyond the listed starters come from the depth-chart order: this is who is most likely in, not a team announcement.

Chiefs offense, 4 WR

  1. LT#70 Kahlil BensonNext up: Jaylon Moore
  2. LG#66 Mike CaliendoNext up: Kingsley Suamataia
  3. C#52 Creed HumphreyNext up: Hunter Nourzad
  4. RG#65 Trey SmithNext up: Mike Caliendo
  5. RT#77 Jaylon MooreNext up: Joshua Ezeudu
  6. WR#4 Rashee RiceNext up: Andrew Armstrong
  7. WR#1 Xavier WorthyNext up: Nikko Remigio
  8. WR#13 Cyrus AllenNext up: Tyquan Thornton
  9. WR#11 Jalen RoyalsNext up: Jeff Caldwell
  10. QB#15 Patrick MahomesNext up: Justin Fields
  11. RB#9 Kenneth Walker IIINext up: Emmett Johnson

49ers defense

  1. LDE#56 Keion WhiteNext up: Romello Height
  2. LDT#92 Osa OdighizuwaNext up: Sebastian Valdez
  3. RDT#99 DeForest BucknerNext up: Gracen Halton
  4. RDE#97 Nick BosaNext up: Mykel Williams
  5. WLB#57 Dre GreenlawNext up: Garret Wallow
  6. MLB#54 Fred WarnerNext up: Tatum Bethune
  7. SLB#53 Jaden DuggerNext up: Luke Gifford
  8. LCB#0 Renardo GreenNo backup listed
  9. SS#36 Marques SigleNext up: Malik Mustapha
  10. FS#27 Ji'Ayir BrownNext up: Ashtyn Davis
  11. RCB#2 Deommodore LenoirNext up: Ephesians Prysock

Defense shown in its base front.

Injury report, Week 16

49ers

No injury report filed for this week yet.

Chiefs

No injury report filed for this week yet.

Special teams

49ers

  1. PK#18 Eddy PineiroNo backup listed
  2. P#15 Corliss WaitmanNo backup listed
  3. H#15 Corliss WaitmanNo backup listed
  4. PR#4 Jacob CowingNext up: Jordan Watkins
  5. KR#19 Deebo SamuelNext up: Jordan James
  6. LS#46 Jon WeeksNo backup listed

Chiefs

  1. PK#7 Harrison ButkerNo backup listed
  2. P#14 Matt AraizaNo backup listed
  3. H#14 Matt AraizaNo backup listed
  4. PR#81 Nikko RemigioNext up: Brashard Smith
  5. KR#81 Nikko RemigioNext up: Brashard Smith
  6. LS#41 James WinchesterNo backup listed